Zoe Oneal

2021-03-07

1. A drug is being tested in a chronic disease whose condition waxes and wanes over time. Which of the following study designs is most effective in evaluating the efficacy and safety of a new therapy

for this disease?

A. Retrospective Cohort

B. Case-Control

C. Prospective, Randomized, Active Control, Parallel Group Design

D. Prospective, Randomized, Active Control, Crossover Design

for this disease?

A. Retrospective Cohort

B. Case-Control

C. Prospective, Randomized, Active Control, Parallel Group Design

D. Prospective, Randomized, Active Control, Crossover Design

Laaibah Pitt

Skilled2021-03-08Added 98 answers

Step 1

There are many different type of studies and different ways of their conduction.

For each of these type of studies,there are crucial features to look for in study design.

Step 2

For studies testing if new interventions are effective it not,most reliable design would be a randomized comparative trial.

In this trial,patients on which studies are going on,are allocated by chance to either the new interventions that is being tested,or the alternative comparative treatment.

Sometimes, comparative treatment is a kind of placebo drug or procedure or sometimes the best treatment available.

Step 3

For testing efficacy of drug treatment, surgical procedure: preferred design is randomized controlled trial

For diagnosis: Combination of randomized comparison of new test with old follow up of cohort

For screening : longitudinal cohort study of patient with Disease

For prognosis: longitudinal cohort study of patient

Causation:case control or cohort study

Step 4

So keeping all the points in mind

Correct option will be

D. Prospective, Randomized, Active Control, Crossover Design

There are many different type of studies and different ways of their conduction.

For each of these type of studies,there are crucial features to look for in study design.

Step 2

For studies testing if new interventions are effective it not,most reliable design would be a randomized comparative trial.

In this trial,patients on which studies are going on,are allocated by chance to either the new interventions that is being tested,or the alternative comparative treatment.

Sometimes, comparative treatment is a kind of placebo drug or procedure or sometimes the best treatment available.

Step 3

For testing efficacy of drug treatment, surgical procedure: preferred design is randomized controlled trial

For diagnosis: Combination of randomized comparison of new test with old follow up of cohort

For screening : longitudinal cohort study of patient with Disease

For prognosis: longitudinal cohort study of patient

Causation:case control or cohort study

Step 4

So keeping all the points in mind

Correct option will be

D. Prospective, Randomized, Active Control, Crossover Design

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