The response area during an analysis of compound A in river water samp

rescuedbyhimw0

rescuedbyhimw0

Answered question

2021-11-16

The response area during an analysis of compound A in river water samples for five replications using HPLC-DAD were tabulated below.
No. of trial12345Area of metoprolol424540428431532
(I) Based on the tabulated data, calculate the % RSD
(II) Comment on the precision obtained from the analysis.

Answer & Explanation

Florence Evans

Florence Evans

Beginner2021-11-17Added 16 answers

Step 1
Formula Used:
Relative standard deviation RSD=100×sx
where, s is the sample standard deviation, and x is sample mean.
Sample Mean x=1ni=Inxi
standard deviation s=(xix){2}n1
Step 2
Solution:
Sample size n=5
Sample Mean x=1ni=Inxi
424+540+428+431+5325
x=471
standart deviation s=(xix){2}n1
(424471)2+(540471)2+(428471)2+(431471)2+(532471)251
s=59.45
Relative standard deviation RSD=100×sx
=59.45471
RSD=12.62
Step 3
Answer:
I). %RSD=12.62
II). There is a precision. Smaller RSD means the data is more precision.

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